PhD Positions in Computational Biology at ETH Zurich

PhD Positions in Computational Biology at ETH Zurich
Employer: Computational Biology Group, ETH Zurich
Location: Basel, Switzerland
Expires: October 30, 2009

Description:

Two PhD positions are available in the Computational Biology Group at the Department of Biosystems Science and Engineering of ETH Zurich in Basel. Our group is engaged in developing mathematical models and efficient algorithms for complex biosystems. We are particularly interested in disease-associated cellular networks and evolutionary dynamics, including genetic and epigenetic variation in cancer and infectious diseases. We seek two PhD students for the following research projects:

1) Analysis of deep sequencing data:

Development and application of statistical models and efficient algorithms for analyzing high-throughput next-generation sequencing data; haplotype inference of mixed virus and tumor samples; human SNP analysis in association studies; RNA-seq and ChIP-seq.

2) Reconstruction of cellular networks from perturbation data:

Probabilistic network reconstruction from RNAi data in the framework of graphical models; experimental design of RNAi screens; network analysis and comparison.

Successful applicants have a strong background in computational biology, mathematics, computer science, statistics, physics, or a related field, and exposure to modeling biological systems. Candidates are expected to engage in interdisciplinary research groups and to foster collaborations with biologists and bioengineers.

The Department of Biosystems Science and Engineering of ETH Zurich is an integral part of SystemX.ch, the Swiss initiative in Systems Biology. It is located in Basel, a European hot-spot for biomedical research, in close proximity of the Biozentrum of the University of Basel, the Friedrich Miescher Institute for Biomedical Research, and the pharmaceutical and biotech industry. ETH Zurich is a major research university, offering an excellent environment for innovative and collaborative research across disciplines.

To apply:

Please send the usual application material, including at least two references, as a single PDF file to niko.beerenwinkel@bsse.ethz.ch (preferred), or via surface mail to:

Prof. Dr. Niko Beerenwinkel

ETH Zurich
Department of Biosystems Science and Engineering
Computational Biology Group
Mattenstrasse 26
CH-4058 Basel
Switzerland